Indian Regulatory Update: Jan-May 2014

JDM update September 2014

Review of international collaborative work International groups have developed tools for the assessment of muscles, as well as the assessment of disease activity and disease damage. This has allowed physicians to standardise their patient assessments. Core outcome variables for JDM have been proposed (IMACS and PRINTO) as well as definitions of disease flare and remission. Work is going on to a...

Liver Transplantation Update: 2014

The first liver transplantation (LT) was performed by Thomas E Starzl five decades ago, and yet it remains the only therapeutic option offering gold standard treatment for end-stage liver disease (ESLD) and acute liver failure (ALF) and certain early-stage liver tumors. Post-liver transplantation survival has also dramatically improved over the last few decades despite increasing donor and reci...

PubChem BioAssay: 2014 update

PubChem's BioAssay database (http://pubchem.ncbi.nlm.nih.gov) is a public repository for archiving biological tests of small molecules generated through high-throughput screening experiments, medicinal chemistry studies, chemical biology research and drug discovery programs. In addition, the BioAssay database contains data from high-throughput RNA interference screening aimed at identifying cri...

Fourier Analysis Jan Wiegerinck version December 3 , 2014

Extramural Update May 2004

Background: Transcriptional regulation plays an important role in the control of many biological processes. Transcription factor binding sites (TFBSs) are the functional elements that determine transcriptional activity and are organized into separable cis-regulatory modules, each defining the cooperation of several transcription factors required for a specific spatio-temporal expression pattern...